LHPVHBR - Hall Pyke

LHPVHBR

LHPVHBR Filter Cartridges

Positive-Charged Zeta PVDF Membrane · Sterile Liquid Filter

LHPVHBR Filter Cartridges feature a modified PVDF membrane that removes a significant level of particles and endotoxins. They are suitable for the sterilized filtration of pharmaceutical liquids including ophthalmic liquids, biological and other diluted preservative solutions.

Features and Benefits

Low extractable and protein binding
Modified PVDF membrane with positive-charged Zeta particles
absorbs small particles and endotoxins
Broad chemical compatibility and temperature resistance
Excellent durability proven by testing forward/reverse pulse up to 100x

Quality Standards

Integrity Test correlates to ASTM F838-05 Bacterial Challenge Test (BCT)
Each filter is individually Integrity Tested prior to leaving the factory
Each filter is Fully Traceable with a unique serial number
Designed, developed and manufactured in compliance with ISO9001
Full Regulatory Compliance with the following:
- 21CFR.210.3(b)(5)(6), 211.72 for Non-Fiber Release
- Endotoxins: <0.25EU/ml/10inch filter
- USP <88> Plastic Class VI-121°C
- FDA 21 CFR177-182 & EU 1935/2004/EC

Typical Applications

Antibiotics Aggressive Solvents
Biological Agents
Blood Products
Chemicals
Cold and Hot WFI
Ophthalmic Solutions
Sanitizing Agents

Flow Rate Characteristics

Materials of Construction

Filter Media	LHPVHBR: Single-Layer Positive-Charged Zeta PVDF Membrane
	DLHPVHBR: Double-Layer Positive-Charged Zeta PVDF Membrane
Support	Polypropylene
Cage/Core/End Caps	Polypropylene

Operating Conditions

Max. Operating Temperature	90°C
Max. Differential Pressure	4.5 bar / 21°C (forward)
	2.4 bar / 90 °C (forward)
Effective Filtration Area	0.58m²/ ϕ 68-10 inch

Sterilization

Inline Steam Sterilization	Forward: up to 30 cycles (135°C for 30min@30kPa per cycle)
Autoclave	up to 30 cycles (130°C for 30min per cycle)

Integrity Test Data

Bubble Point	BP: ≥ 0.32 MPa(water) ,LHPVHBR(0.45+0.22 um)
Diffusion Flow	DF: ≤ 20 mL/min/10″ @0.28 Mpa(water),LHPVHBR(0.45+0.22 um)

Ordering Information

LHPVHBR [Single-Layer]	Removal Ratings	End Cap	Nominal Length	Seal Material
	0010=0.1μm	HSF=226 /Fin (PBT Insert)	05= 5″	S=Silicone
	0022=0.22μm	HSC=226 /Flat (PBT Insert)	10=10″	E=EPDM
	0045=0.45μm	HTF=222 /Fin (PBT Insert)	20=20″	V=Viton
		HTC=222 /Flat (PBT Insert)	30=30″
		DOE=Double Open End	40=40″
DLHPVHBR [Double-Layer]	2222=0.22+0.22μm
	2245=0.22+0.45μm
	6545=0.65+0.45μm

Downloads

File	Description	File size	Downloads
Hall Pyke LHPVHBR		2 MB	910